Published: Thu, December 06, 2018
Health Care | By Oscar Goodwin

Doctors Announce First Ever Baby Born From Uterus Transplanted From Dead Body

Doctors Announce First Ever Baby Born From Uterus Transplanted From Dead Body

The demonstrated success of a procedure involving a deceased donor, he says, may spare live donors from undergoing risky procedures, and make transplants possible for far more women.

The girl born in the Brazilian case was delivered via caesarean section at 35 weeks and three days, and weighed 2,550 grams, the case study said. She became pregnant after just one embryo transfer. He also tried the procedure on a second Brazilian woman, but she had to have the uterus removed two days after the operation because of complications.

There have been 39 womb transplants using a live donor, including mothers donating their womb to their daughter, resulting in 11 babies.

Five months before the transplant, the recipient had sixteen eggs from her own functional ovaries removed.

In what could prove to be a major advancement for couples facing infertility, the first baby born from a deceased donor uterus transplant was successfully completed at the University Of Sao Paulo School Of Medicine in Brazil, according to a report in the scientific journal Lancet.

Eleven previous births have used a transplanted uterus, but they were from a living-not a deceased-woman, who was usually a relative or a friend, according to The Associated Press.

The transplant took place in September of 2016.

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"The Brazilian group has proven that using deceased donors is a viable option", said the clinic's Dr. Tommaso Falcone, who was involved in the OH case.

In 2016, doctors at the Cleveland Clinic in OH transplanted a uterus from a deceased donor, but it failed after an infection developed.

The donor was 45 years old and died of bleeding on the brain, caused by a stroke.

In all those cases, the uteruses came from living women - often a family member or friend of the recipient.

These are still early days for uterine transplants, says Kate O'Neill, co-lead investigator for the University of Pennsylvania's uterus transplant program, who was not part of the work in Brazil.

An estimated one in 500 women have no wombs or abnormal wombs due to hysterectomies, inherited disease, malformation or infection.

The surgical team had to connect the donor's uterus with the veins, arteries, ligaments, and vaginal canal of the recipient.

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"The numbers of people willing and committed to donate organs upon their own deaths are far larger than those of live donors, offering a much wider potential donor population", he added.

"I don't know that they're highlighted enough when we're celebrating these kind of breakthroughs", she said.

Is a uterus transplant permanent?

"Up till now it was not known that uterus can survive more than four hours out of a living body, however, the present case shows that the uterus is a quite strong an organ", Ms Sharma said.

However, he cautioned: "Uterine transplantation is a novel technique and should be regarded as experimental".

But out of the 10 womb transplants from deceased donors, none of the procedures has resulted in a birth - until now.

Before uterine transplants, these women could only adopt children, or use a surrogate. Fifteen were fertilised, with 8 resulting in embryos that were subsequently preserved for later implantation.

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