Published: Fri, June 15, 2018
Health Care | By Oscar Goodwin

Medications May Increase Risk Of Depression

Medications May Increase Risk Of Depression

The list includes a wide range of commonly taken medications.

Still, the findings are supported by previous research that has found links between depression and specific classes of prescription medications, such as proton pump inhibitors and hormonal contraceptives. "It could be the chronic conditions people are taking the medications for, heart conditions, cancer, is what's really causing the depression, not the drugs", said Dr. Tara Narula.

For the study, Quato and her colleagues analyzed information provided by more than 26,000 USA adults who participated in the National Health and Nutrition Examination Survey (NHANES) from 2005 through 2014. They were asked to list out the medications they were consuming during the time of the survey.

Researchers cautioned that the survey approach meant conclusions could not be drawn about cause-and-effect, and that questionnaires did not account for a history of depression. The topic of suicide and depression has been thrust into the spotlight following two celebrity deaths and a startling CDC report last week.

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Olfson said, "What we found is that, in fact, they're more likely".

"Even if the same doctor is prescribing drugs, the fact is that it's really hard - there's no software that tells a doctor, 'your patient is on three drugs that predispose them or are associated potentially with depression or suicidal symptoms", Qato said.

Fifteen percent of participants who used three or more of these drugs at once were depressed compared to lower rates for those who only used one.

On the other hand, there's a worrisome dose-response pattern: the more of these drugs patients took concurrently, the higher their risk of depression.

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Mordecai says, if you start a new medicine it can be helpful to keep track of changes in how you feel.

Prevalence of depression higher for adults reporting use of multiple meds with depression as side effect.

It's also worth having a conversation with your doctor about whether you might be able to stop a medication, Mordecai says. Basically, the rates of depression were fairly low for those on just one of those medications - about 7% experienced depression - but the number more than doubled to about 15% for patients on three or more of these medications.

"Many may be surprised to learn that their medications, despite having nothing to do with mood or anxiety or any other condition normally associated with depression, can increase their risk of experiencing depressive symptoms, and may lead to a depression diagnosis", lead author Dima Qato, assistant professor of pharmacy systems, outcomes and policy at the University of IL at Chicago told the news agency AFP.

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Qato said that pharmacists stick labels on pill bottles, warning that drugs increase the risk of drowsiness, that people should take food or not drink alcohol with a certain medication, but that many patients - and doctors - may be unaware of the depression risks of certain prescription drugs.

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