Published: Wed, January 10, 2018
Health Care | By Oscar Goodwin

Ibuprofen may increase risk of fertility issues in men, study suggests

Ibuprofen may increase risk of fertility issues in men, study suggests

Male fertility is dropping around the world and the researchers wanted to see if ibuprofen might be contributing to this.

Scientists warn that ibuprofen could be wrecking men's fertility by making their balls shrivel up.

The findings by French and Danish researchers followed a six-week clinical study involving 31 men between the ages of 18 and 35.

While reducing pain signals in the brain, ibuprofen also lowers the male sex hormone testosterone.

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Doctors in Copenhagen who led the study said that while the disorder was mild and temporary in the volunteers, they feared it could become permanent in long-term ibuprofen users.

The condition is normally seen in older men and smokers, and is caused by the body having to boost testosterone levels because normal production in the testes is insufficient.

Ibuprofen is one the most well-known pain medications in the West, taken by millions of people every day. In the group, the men who took 600 mg of Ibuprofen (the equivalent of three tablets) twice a day developed a condition called compensated hypogonadism.

The authors of the study point to the wide range of endocrine disorders that may result from fluctuations in or impairment of the pituitary-gonadal axis such as infertility, depression, heart disease, arthritis and diabetes. After 44 days, levels were even higher.

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'Therefore it is also of concern that men with compensated hypogonadism may eventually progress to overt primary hypogonadism, which is characterised by low circulating testosterone and prevalent symptoms including reduced libido, reduced muscle mass and strength, and depressed mood and fatigue'. The higher and longer the level of exposure, the researchers found, the more dramatic the impact.

Oh no! A new study shows that ibuprofen can have a negative effect on male fertility!

A study of nearly 1,000 men tracked for seven years found that twice as many with hypogonadism died as did those with normal testosterone levels. This amount was used to represent the dose taken by athletes to manage pain.

According to the results of their study, taking aspirin, acetaminophen or ibuprofen during pregnancy can lead to complications with regards to the development of babies.

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Before now, he says, "most warnings regarding this family of painkillers have focused on limiting long-term use in the elderly to prevent gastrointestinal, renal and cardiac adverse effects".

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